Are you referring to combustion chamber volume or port volume?

It would really have to depend on the rest of your engine combination as to whether it would be a good scenario or a bad scenario. Of course chamber size affects your compression ratio, along with piston shapes, deck heights, head gaskets, etc.

Port volume also affects the engine combination extensively. If you have a small displacement engine with a small cam, dual plane intake, etc., then a large volume is going to adversely affect the performance. That large volume of air has a momentum and velocity...it's harder to get a large amount of air moving in a short amount of time. A tunnel port head on a small displacement engine, IMO, would be better suited for higher rpm operation.

For a given combination, I try to maximize flow while keeping port volume lower.